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To achieve tissue-wide Gls depletion, Tubulin-Gal4 virgins were crossed to UAS-Gls-RNAi males

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In agreement with the findings that upregulated proteins in cancer are known to transport GSH, it has been proposed that GSH may play a role in the regulation of GPx3 activity

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doi:10.1056/NEJMoa1606599 Peker Y, Glantz H, Eulenburg C, Wegscheider K, Herlitz J, Thunstrom E

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